Research Focus

I am interested in the role of catecholamines in modulating the expression of parental behavior

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Research Focus

Research Focus

Neuroendocrine signalling in Drosophila Melanogaster.

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Repair and regeneration following traumatic brain injury; Neuregulin-1

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Development of the neocortex, Fetal alcohol spectrum disorders.

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Neural mechanisms underlying avoidance behavior in insects.

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My interest in research include how peripheral inflammatory responses can influence the central nervous system, particularly in the gut-brain axis and how viral infections cause brain pathologies.

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Research Focus

Latrophilins, a class of molecules known as synaptic cell adhesion molecules were recently shown to physically connect pre- and post-synaptic membranes controlling excitatory synaptic development in hippocampal neurons,.
Where alternatively spliced Latrophilins cause inhibitory synaptogenesis. Latrophilin 2 was shown to control synaptogenesis in the hippocampus arising from the main input to the hippocampus, the entorhinal cortex and Latrophilin-3 controls the other main input arising from CA3. In the lab we use a variety of techniques ranging from viral mediated gene deletion, circuit tracing, single neuron reconstructions and RNA analysis using cutting edge quantitative single molecule In-situ hybridization. The goal is to ascertain data ranging from mRNA expression to protein to circuit assembly and behavioral analysis of circuit mediated learning. Using these highly precise methodologies we seek to better understand the molecules that control how the brain is wired and how their misfunction might be involved in pathology.

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Research Foucs

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Research Focus

Effects of noise induced hearing loss in the auditory cortex

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Research Focus

I am interested in studying executive function and inhibitory control in humans using fMRI.

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Neuromodulation in sensory perception.

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Neuronal circuitry guiding gustatory behavior in Drosophila and its intersection with metabolic control

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Research Focus

Neural activation following olfactory-mediated defensive behaviors

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Neural-Immune signaling following brain injury

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The role of sub-regional specialization and connectivity of the medial prefrontal cortex in the acquisition and expression of contextual fear memory

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My current research focuses on Fragile X Syndrome. In human, FXS patients represent hypersensitivity to sound, and this characteristics is measured by audiogenic seizures in animal models. My goal is to see if Fmr1 knock-out mice (a mouse model of FXS) will display sound hypersensitivity as human beings by designing a new behavior paradigm (less drastic than audiogenic seizures). And if that's the case, I'll further pursue the behind mechanisms.

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Molecular mechanisms of pruning

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Research Focus

The endocannabinoid system, vagus nerve signaling, gut-brain axis

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Research Focus

Understanding the neuronal mechanism underlying animal's behavior, such as paying attention and making decisions.

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Research Focus